M.V. Burmistrov1, 3, A.I. Ladur2, E.K. Kulbida1
1Kazan (Volga Region) Federal University, Kazan
2Republic Cancer Center named after Prof. G.V. Bondar, DNR, Donetsk
3Republic Clinical Hospital, Kazan
Burmistrov M.V. – MD, Deputy Chief Doctor, Professor, Head of the Department of Surgical Diseases for post-graduate education
74 Karl Marx St., 420012 Kazan, Russian Federation, tel.: +7-917-869-53-07, е-mail: burma71@mail.ru, ORCID ID: 0000-0002-5334-6481
Abstract. Non-small cell lung carcinoma (NSCLC) is one of the most prevalent and aggressive types of malignancy, accounting for approximately 17% of all cancer cases, making it a critical area of investigation in oncology and thoracic surgery. According to the World Health Organization (WHO) data, lung cancer holds a prominent position in terms of morbidity and mortality rates, underscoring the importance of developing effective strategies for early detection and treatment. In recent years, there has been a rise in the incidence of NSCLC, linked to an increase in risk factors such as environmental pollutants and genetic predispositions, as well as chronic respiratory conditions. In light of this, the development of advanced surgical techniques, including bronchoplastic operations aimed at preserving lung function through bronchial resection and the creation of interbronchial anastomoses, is of paramount significance. Despite the development and improvement of advanced diagnostic and therapeutic techniques, the outcomes of treatment for LC patients continue to be disappointing, with a 5-year survival rate of only 15–16%. Timely surgical intervention remains the key to improving patient survival. At present, a combination of complex therapeutic approaches is employed in the management of lung cancer, with surgery playing a pivotal role. The most promising approach involves organ-sparing surgical interventions, including combined ones, which not only maintain long-term outcomes but also significantly improve functional outcomes and quality of life for patients. Among these, complex organ-sparing procedures such as combined bronchoplastic lung resections involving resection of the pulmonary artery, pericardium, and tracheobifurcation represent the pinnacle of surgical expertise. These surgical procedures enable the complete eradication of tumors and regional metastases, while ensuring minimal damage to unaffected tissues. This is a crucial aspect of the organ-sparing approach to treatment. The present study delves into the analysis of both immediate and long-term outcomes of combined bronchoplastic lung resections aimed at preserving the organ.
Key words: non-small cell lung cancer, bronchoplastic lobectomy, pulmonary artery reconstruction, postoperative complications, long-term results.