S.V. Smetanina1, E.N. Slavnova², N.Yu. Orlinskaya3, M.B. Danyaeva1, S.B. Korolkova¹
1Nizhny Novgorod Regional Clinical Oncology Center, Nizhny Novgorod
2Moscow Cancer Research Institute named after P.A. Herzen — branch of the National Medical Research Radiological Center, Moscow
3Privolzhsky Research Medical University, Nizhny Novgorod
Smetanina Svetlana V. — Cand. of Sci. (Med.), Head of the Cytological Laboratory of the Nizhny Novgorod Regional Clinical Oncology Center
11/1 Delovaya Str., Nizhny Novgorod, 603163, Russian Federation, tel. +7-904-781-70-60, e-mail: firstname.lastname@example.org, ORCID ID: 0000-0002-7000-5910
Abstract. Differential bone marrow cell count is a fundamental step in diagnostic hematology. The identification of metastatic carcinoma cells in sternal aspirates can be technically difficult with routine microscopy. Due to the morphological similarity of poorly differentiated carcinoma cells with young hematopoietic cells, the fact of metastasis can be easily missed or misinterpreted. It is even more difficult to detect micrometastases due to their uneven distribution over the smear, especially outside the imaging area, which leads to an erroneous diagnosis.
Key words: cytological diagnostics, sternal punctate, cell blocks.