A.V. Yarikov1-5, A.O. Dubskikh6, I.I. Smirnov3, A.P. Fraerman3,7, V.V. Khinovker8-10, O.A. Perlmutter3,7, A.G. Sosnin1, S.F. Kuznetsov11, R.M. Kabardaev11, A.S. Mukhin7

1Privolzhsky district Medical Center FMBA, Nizhny Novgorod

2Central medical and sanitary unit №50 FMBA of Russia, Sarov

3City Clinical Hospital №39, Nizhny Novgorod

4City Clinical Hospital №13, Nizhny Novgorod

5Central City Hospital of Arzamas, Arzamas

6Sverdlovsk Regional Oncology Dispensary, Ekaterinburg

7Volga Research Medical University, Nizhny Novgorod

8Federal Siberian Scientific and Clinical Center FMBA of Russia, Krasnoyarsk

9Clinical Hospital №51 FMBA of Russia, Zheleznogorsk

10Krasnoyarsk State Medical University named after Professor V.F. Voyno-Yasenetskiy, Krasnoyarsk

11National Medical Research Center of Oncology named after N.N. Blokhin, Moscow

Yarikov Anton V. ― Cand. of Sci. (Med.), neurosurgeon/orthopedic traumatologist of Privolzhsky District Medical Center of FMBA, City Clinical Hospital №39, City Clinical Hospital №13 of Nizhny Novgorod, Central City Hospital of Arzamas, Central medical and sanitary unit №50 FMBA of Russia, Sarov

2 Nizhne-Volzhskaya Emb., Nizhny Novgorod, 603001, Russian Federation, e-mail:, SPIN-code: 8151-2292, ORСID ID: 0000-0002-4437-4480

Abstract. In most cancer patients, a step-by-step scheme of anesthesia is effective, but in 20-30% of patients it is not possible to achieve an acceptable level of analgesia, despite the use of various combinations of analgesics in them. The article considers the problem of analgesic therapy in cancer patients. The main causes and characteristics of pain in oncological practice are presented. The preparations for use in the clinical practice of palliative oncology, taking into account oncological pain, are given. All modern surgical methods for the treatment of pain syndromes in oncological practice are presented. The coverage of this problem, among other things, is aimed at attracting the attention of doctors, since their use makes it possible to reduce or stop the pain syndrome in this group of patients and improve their quality of life.

Key words: oncological pain, neurolysis, chronic pain syndrome, pain control, neuromodulation, radiation therapy, pulsed radiofrequency ablation, spinal cord stimulation.