Sh.Kh. Gantsev2, K.V. Menshikov1,2

Nasretdinov1, N.I. Sultanbaeva1

1Republican Clinical Oncological Dispensary, Ufa

2Bashkir State Medical University, Ufa

Menshikov Konstantin V. ― Ph.D. (medicine), Associate Professor of the Department of Oncology with courses on oncology and pathological anatomy of the Bashkir State Medical University; oncologist of the Department of Chemotherapy of the Republican Clinical Oncological Dispensary

73/1 Oktyabrya Ave., Ufa, Russian Federation, 450054, tel. +7-917-348-82-51, e-mail:, ORCID ID: 0000-0003-3734-2779

Abstract. Melanoma is one of the most malignant tumors. A common localization of melanoma is the skin, but the mucous membranes of other organs can also be affected by this tumor. In turn, malignant neoplasms of the vulva are quite rare, they account for less than 1% of malignant neoplasms in women. Primary vulvar melanoma is an important subgroup of malignancies with differences in biology. Molecular-genetic characteristics of melanoma of the vulva differ in the mutational characteristics of melanoma of the mucous membranes and skin. According to some authors, vulvar melanoma should be considered as a separate nosological unit. This may allow us to develop approaches to early diagnosis and adequate treatment, which in turn will improve the long-term results of this category of patients.

Key words: vulvar melanoma, surgical treatment, vulvectomy, inguinal-femoral lymphadenectomy, sentinel lymph node.