Introduction. Recently, patients with distant metastases were considered inoperable and had to rely on palliative systemic chemotherapy. However, with the development of new technologies and minimally invasive operations the boundaries of curable have expanded. One of these new technologies used in the treatment of patients with lung neoplasm who had contraindications to the surgery is radiofrequency ablation. In this article we analyzed the complications of radiofrequency ablation.

Materials and methods. 421 radiofrequency ablation were performed in 268 patients from 2007 to 2015.

Results. Complications occurred in 78 (29.1%) patients. Complication grade 2 and 3a (Clavien classification) were observed in 74 (27.7%) patients, and 3b and 5 ― in 4 patients (1.4%). Patients with grade 4 complications were not recorded. We assessed the impact on the development of complications such factors as gender, age, morphology, multiple ablations, the location and size of the tumor, comorbidity, simultaneous transthoracic biopsy and preoperative radiation or chemotherapy. A significant impact on the complications have only: multiple ablation, the tumor localization and the chronic obstructive pulmonary disease as comorbid condition.

Conclusion. Radiofrequency ablation is a relatively safe treatment for patients with inoperable malignant tumors of the lung. Gender, age, tumor size, morphology, combination with biopsy and preoperative radiation or chemotherapy does not affect the incidence of complications.

Key words: radiofrequency ablation, complications, lung cancer, lung metastases. 


D.G. Korolev1, S.V. Kozlov2, O.I. Kaganov1,2, E.P. Krivoschekov2, A.M. Tyulyusov1

1Samara Regional Clinical Oncology Center, Samara

2Samara State Medical University, Samara


Korolev D.G. ― interventional radiologist in Samara Regional Clinical Oncology Center

50 Solnechnaya Str., Kazan, Russian Federation, 443031, tel. +7-927-200-35-48, e-mail: