EFFECTIVENESS OF DIFFERENT DIAGNOSTIC METHODS OF PROSTATE CANCER DETECTION

УДК 616.65-006.6-07

I.B. Chigireva1, R.Sh. Khasanov2, S.V. Panchenko1, M.G. Sharafutdinov3
1Regional Clinical Oncology Center, Ulyanovsk
2Kazan State Medical Academy, Kazan
3Ulyanovsk State University, Ulyanovsk

Chigireva I.B. ― Deputy chief physician for organizational and methodical work of the Regional Clinical Oncology Center

90 12 Sentyabrya St., Ulyanovsk, Russian Federation, 432017, tel.: (8422) 32-61-03, +7-927-818-16-76, e-mail: inchy08@yandex.ru 

Abstract. A prostate cancer is one of the most widespread malignant tumor at men from all over the world. Article represents the review of modern methods of diagnosis of prostate diseases. This definition a prostate-specific antigen test, digital rectal examination, transrectal ultrasonography, sonoelastography, urinary prostate cancer antigen 3. Sensitivity and specificity of each method is shown.

Key words: prostate cancer, prostate-specific antigen, digital rectal examination, urinary prostate cancer antigen 3, sonoelastography, РСА3.

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CLINICAL REPORT OF BRCA-ASSOCIATED BREAST CANCER AMONG REPRESENTATIVE OF THE TATAR NATIONALITY GROUP

УДК 616-006.66:618.11-006.6:575.113:575.224.2

A.I. Khasanova1,2, M.G. Gordiev1,2, E.Yu. Ratner¹, V.V. Zhavoronkov1,2, R.Sh. Khasanov1,2, A.G. Nikitin4  
1Tatarstan Cancer Center, Kazan
2Volga Region branch of N.N. Blokhin Russian Cancer Research Center, Kazan
3Kazan State Medical Academy, Kazan
4Federal Scientific Clinical Center of Specialized Types of Medical Care and Medical Technologies FMBA of Russia, Moscow

Khasanova A.I. ― Cand. Med. Sc., oncologist of the Tatarstan Cancer Center
29 Sibirskiy Trakt, Kazan, Russian Federation, 420029, tel. (843) 525-73-97, e-mail: haalfy@gmail.com

Abstract. During medical and genetic counseling of representative of the tatar nationality group with anamnesis of breast cancer and ovarian cancer, as well as a family history of cancer in exon 10 of BRCA1 gene was detected nucleotide substitution s.915T>A in heterozygous state. With direct sequencing method were automatically analyzed exons 2, 4, 5, 10, 12-17 and adjacent intronic regions of BRCA1 gene. This replacement is not described in the databases BRCA Share, Breast Cancer Information Core database, LOVD, HGMD Professional and can be classified as previously not published disease-causing mutation leading to premature termination of translation.

Key words: breast cancer, ovarian cancer, mutations and polymorphisms of BRCA1/2 gene, ethnogeographical features of distribution, tatar population.

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VIDEO-ASSISTED THORACOSCOPY IN THE TREATMENT OF BINING SUBMUCOSAL ESOPHAGEAL MALIGNANCY

УДК 616.329-006.363.03-089.87

E.I. Sigal, Rodion E. Sigal, M.V. Burmistrov, Roman E. Sigal

Tatarstan Саnсеr Center, Kazan

Sigal Rodion E. – oncologist of the Тatarstan Саnсеr Center

29 Sibirskiy Trakt, Kazan, Russian Federation, 420029, tel.: (843) 519-27-38, +7-927-248-33-35, e-mail: rodion_sigal@mail.ru

Abstract. We analysed video-assisted thoracoscopy (VATS) in diagnosing and treatment of esophagus leiomyoma (LE). 15 VATS esophagus operations were performed in Tatarstan Cancer Center from 1997 to 2015 concerning leiomyoma. The average age is 48,1 (26-74). Mostly men have been operated ― 9 people, women ― 6 people. Among these leiomyoma has been localized in 2 patients in the upper esophagus, in 10 patients ― in the middle part, and in 3 patients ― in the lower part. Postoperative lethality hasn’t been observed. Conversion wasn’t needed. Showing the technical aspects of surgery. They discussed the results of the postoperative period.

Key words: thoracoscopy (VATS), esophagus leiomyoma, esophagus, benign submucosal esophageal malignancy, complications.

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ENDOBRONCHIAL ULTRASONOGRAPHY IN PATHOLOGY MEDIASTINUM RESPIRATORY SYSTEM

УДК 616.24-006-072 V.N. Korolev1, M.S. Burdyukov2,3, I.Yu. Surovtsev1, E.A. Sazhina4 1«EVIMED» Ltd., Chelyabinsk 2N.N. Blokhin Russian Cancer Research Center, Moscow 3Russian Medical Academy of Postgraduate Education of Russian Ministry of Healthcare, Moscow 4Regional Clinical Hospital №3, Chelyabinsk   Korolev V.N. ― Cand. Med. Sc., Deputy Director, Endoscopist «EVIMED» Ltd. 9B Blucher St., bld. 10/22, Chelyabinsk, … Читать далее

EFFICIENCY OF MAMMOGRAPHY SCREENING, ESTIMATES OF RESULTS AMONG WOMEN IS YOUNGER THAN 50 YEARS OF KHANTY-MANSIYSK

УДК 618.19-006.6-07(571.122-25) Yu.A. Belaya1,2, N.A. Zakharova1 1Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk 2District Clinical Hospital, Khanty-Mansiysk State Cancer Center, Khanty-Mansiysk Belaya Yu.A. ― postgraduate student of the Department of Oncology, Radiodiagnosis and Radiation therapy of Khanty-Mansiysk State Medical Academy, oncologist of the oncology department №2 of District Clinical Hospital, Khanty-Mansiysk State Cancer Center 40 Kalinin St., … Читать далее