F.T. Nosirova, S.G. Umarova, N.I. Bazarov
Nosirova F.T. – PhD (Medicine), Assistant Lecturer of the Oncology Department
Dushanbe, Republic of Tajikistan, tel.: +992902040707, e-mail: firuzka.nosirova.t@mail.ru
The purpose – to study clinical features, diagnosis, and treatment of stage III ovarian cancer.
Material and methods. An analysis of domestic and foreign scientific literature devoted to the clinical issues, diagnosis, and treatment of stage III ovarian cancer was carried out.
Results and discussion. Based on the study of 106 scientific publications devoted to the clinical issues, diagnosis, and treatment of stage III ovarian cancer, we found that one of the important factors influencing the survival of patients with advanced ovarian cancer is the implementation of cytoreductive surgery in full or optimal volume. The standard for the treatment of OC is considered to be surgery followed by platinum-containing chemotherapy. Preoperative chemotherapy followed by interval cytoreductive surgery has not lost its role in the treatment of OC. According to modern literature data, the criteria for selecting patients into the group of primary or interval cytoreductive surgery have not yet been determined and the issue of choosing a primary treatment tactic is becoming the most discussed among oncologists treating this category of patients.
Conclusion. Rational assessment of clinical manifestations, life history and disease, consistent use of radiological (CT, NMR), morphological methods for stage III ovarian cancer are a rational path to timely recognition and adequate treatment of the disease.
Key words: stage III malignant ovarian tumors, clinical picture, diagnosis, evaluation of treatment effectiveness, oncology, gynecology.