S.V. Kotelnikova1, 3, D.P. Kovtun1, 3, O.G. Polushin1, G.N. Khrykov2, 4, A.A. Bublikova1, O.E. Zenko1, E.V. Shcherbakova1, D.Yu. Boyarinov2, 5, M.N. Myanzelin2, P.Yu. Tsuprun2
1Central Pathological Department of General Pathology of the Leningrad Region Bureau of Forensic Medicine, Saint Petersburg
2Leningrad Regional Clinical Hospital, Saint Petersburg
3Saint-Petersburg State Pediatric Medical University, Saint Petersburg
4Almazov National Medical Research Center, Saint Petersburg
5North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg
Kotelnikova S.V. — doctor of the Central Department of Pathology and Anatomy, Assistant Lecturer of the Department of Pathology Anatomy
7 Santiago de Cuba St., 194291 Saint Petersburg, Russian Federation, tel.: +7-910-974-48-48, e-mail: snezhana.kotelnikova.98@mail.ru, ORCID ID: 0009-0000-2418-2572
Abstract. Gallbladder malignant melanoma is a rare disease, mainly secondary. Malignant melanomas rarely metastasize to the gallbladder, but they are registered most often among secondary tumors of this organ, which should be taken into account in differential diagnosis. Primary malignant melanoma of the gallbladder is extremely rare: about 40 cases have been described in the specialized literature since 1907. A lifetime diagnosis of primary gallbladder malignant melanoma is a diagnosis of exclusion that requires a comprehensive examination of the patient, histological and immunohistochemical confirmation of the neoplasm histogenesis. The clinical case of primary gallbladder melanoma in a 57-year-old woman is presented. Diagnosis was made after a routine pathological and anatomical examination of the cholecystectomy material and additional clinical examination.
Key words: malignant melanoma, gallbladder, diagnosis, treatment