N.G. Semikoz1,2, A.S. Chegonenko2
1G.V. Bondar Republican Cancer Center, Donetsk
2Donetsk State Medical University named after M. Gorky, Donetsk
Semikoz Nataliya G. ― Doct. of Sci. (Med.), Professor of the Department of Oncology and Radiology named after Acad. G.V. Bondar of the Donetsk State Medical University named after M. Gorky, Head of Radiology Department №3 of the G.V. Bondar Republican Cancer Center
2a Polotskaya Str., Donetsk, 283092, Donetsk People’s Republic, Russian Federation, tel. +7-949-334-77-93, e-mail semikoz@interdon.net, ORCID ID: 0009-0004-9229-732X
Abstract. Treatment of brain tumors remains an urgent problem due to the variability of histological forms and localization features. Classical methods of treatment have been demonstrating effectiveness for decades, but they do not allow achieving the maximum possible effect. CNS tumors continue to be associated with unfavorable outcomes and low survival. Efficiency improvement is possible through the introduction of a personalized approach to the treatment of such patients. The article is devoted to the review of existing methods of diagnosis and treatment of tumors of this localization ― from the earliest to the most modern. Special attention is paid to the radiotherapeutic aspect, the introduction of which, both in combination with other areas of treatment and an independent method, significantly increases the duration and quality of life of patients. The use of a split course of radiotherapy with drug support is reasonably appropriate and allows patients to tolerate treatment more easily, without pronounced radiation reactions and complications. Radiotherapy can be used both for tumors of high and low malignancy, as well as for relapses, non-radical removal of the tumor, or if the patient refuses surgical treatment.
Key words: brain tumor, radiotherapy, radiation diagnostics, immunotherapy, immunohistochemistry, chemotherapy, neurosurgery.