ICG MAPPING OF SENTINEL LYMPH NODES IN ENDOMETRIAL CANCER. LITERATURE REVIEW AND OUR APPLICATION EXPERIENCE

L.M. Nigmatullin, I.I. Khusainova, A.D. Khaziev

Naberezhnye Chelny Branch of the Republican Clinical Oncology Dispensary of Ministry of Healthcare of Tatarstan Republic named after prof. M.Z. Sigal, Naberezhnye Chelny

Khusainova Ilyuza I. ― Cand. of Sci. (Med.), oncologist, head of palliative care department №3 of the Naberezhnye Chelny Branch of the Republican Clinical Oncology Dispensary of Ministry of Healthcare of Tatarstan Republic named after prof. M.Z. Sigal

18A Naberezhnochelninskiy Ave., Naberezhnye Chelny, 423803, Russian Federation, tel. +7-987-236-31-44, e-mail: kh.ilyuza@gmail.com, SPIN-code: 2126-1310, Researcher ID: 8425-2023, ORCID ID: 0000-0002-1655-2905

Abstract. In modern medical oncology, special attention is paid to «personalized» medicine, which implies a strategy to increase efficiency with the help of targeted therapy. Similar attempts to achieve accuracy are being made in oncosurgical practice. Sentinel lymph node (SLN) mapping is being actively implemented in the surgical staging of endometrial cancer. ICG mapping of the SLN can reduce the morbidity associated with regional lymphadenectomy while providing equivalent prognostic information about the status of the lymph nodes. The experience of using indocyanine green in our clinic of patients with endometrial cancer of low and moderate risk of lymphovascular invasion to identify sentinel lymph nodes seems to be promising in providing adequate intraoperative staging. The introduction of this technique into the management will significantly reduce the risk of postoperative complications associated with lymphadenectomy, without affecting to the prognosis of the disease.

Key words: endometrial cancer, sentinel lymph node mapping, indocyanine green, regional lymphadenectomy, literature review.