A.V. Yarikov1,2, A.A. Boyarshinov2, I.A. Lobanov2, A.O. Dubskikh5, O.A. Perl'mutter2, A.P. Fraerman2, A.G. Sosnin1, S.F. Kuznetsov4, R.M. Kabardaev4

1Privolzhsky District Medical Center of FMBA, Nizhny Novgorod

2City Clinical Hospital №39, Nizhny Novgorod

3Volga Research Medical University, Nizhny Novgorod

4Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation, Moscow

5Sverdlovsk Regional Oncological Dispensary, Ekaterinburg

Yarikov Anton V. ― Cand. of Sci. (Med.), neurosurgeon/orthopedic traumatologist of Privolzhsky District Medical Center of FMBA and City Clinical Hospital №39

2 Nizhne-Volzhskaya Emb., Nizhny Novgorod, 603001, Russian Federation, e-mail:, SPIN-code: 8151-2292, ORСID ID: 0000-0002-4437-4480

Abstract. Multiple myeloma accounts for about 1% of all malignant tumors and 10-13% of all hematological tumors. In 3-5% of cases, myeloma occurs in people younger than 45 years and practically does not occur in childhood and adolescence. The mortality rate from myeloma is 18% of all hematological tumors. The paper presents the clinical picture of this disease: aching bone pain, pathological fractures, hypercalcemia, nephropathy, polyneuropathy, etc. Further, the article describes modern instrumental methods of diagnosis and treatment. The authors focused special attention on surgical methods of treatment of myeloma: vertebroplasty, kyphoplasty, decompression, decompression-stabilizing interventions. The results of the above-mentioned methods of treatment according to modern specialized literature are presented. Currently, preference is given to percutaneous and minimally invasive interventions. With multiple myeloma, early diagnosis and treatment of these patients should be first of all with a hematologist.

Key words: multiple myeloma, myeloma, vertebroplasty, plasmocytoma, Bence-Jones protein, myeloma, chemotherapy.