SHORT-TERM AND LONG-TERM RESULTS OF TREATMENT OF PATIENTS WITH RETROPERITONEAL TUMORS

O.I. Kaganov1,2, A.Е. Orlov1, K.V. Samoylov2, N.V. Blinov2

1Samara State Medical University, Samara

2Samara Regional Clinical Oncology Dispensary, Samara

Kaganov Oleg I. ― MD, Professor of the oncology department of the Samara State Medical University; Deputy chief physician for scientific work of the Samara Regional Clinical Oncology Dispensary

89 Chapaevskaya Str., Samara, Russian Federation, 443099, tel. (846) 994-76-26, e-mail okaganov@yandex.ru, SPIN-code: 2705-4187

Abstract

Aim ― to evaluate early and long-term results of surgical treatment of patients with retroperitoneal tumor.

Material and methods. From 2008 to 2015 the treatment of 187 patients with the diagnosis of primary retroperitoneal tumor was analyzed. All patients were divided into 3 groups: in the first group patients (115) got tumor removal within the healthy tissues, in the second (61) ― combined tumor removal. In the third group before combined tumor removal in preoperative period patients (11) got embolization of tumor supply vessels.

Results. Early results in the first two groups of compare: intraoperative blood loss 281,33±110,94 ml and 410,91±113,31 ml, operation time ― 58,33±27,14 min. and 185,15±32,49 min., postoperative complications ― 7 (6,08%). In the third group intraoperative blood loss was 121,33±27,94 ml, the time of operation ― 43,13±16,11 min., postoperative complications 1 (4,5%). Recurrences after surgical treatment revealed in 63 (66,3%) patients with malignant forms of retroperitoneal tumor, one-year survival rate ― 41%, three-year survival rate ― 8%, overall survival median reached 11 months.

Conclusion. After the combined removal of the retroperitoneal tumor, intraoperative blood loss, operation time, the number of postoperative complications, and postoperative LOS were significantly greater in comparison with the group of patients where the tumor was removed within healthy tissues. The method of preoperative embolization of the tumor feeding vessels can reduce intraoperative blood loss, the time of operation, the number of postoperative complications, mortality rate and LOS.

Key words: retroperitoneal tumors, surgical treatment, combined treatment, embolization, treatment results.