CLINICAL AND ANATOMICAL ASPECTS OF INTRAORGAN LYMPHATIC METASTASING OF PRIMARY LUNG CANCER.

УДК 611.24:616.24-006.6:616-033.2         

I.I. Kagan, S.V. Pinchuk

Orenburg State Medical University, Orenburg

Orenburg Regional Clinical Oncology Center, Orenburg

Pinchuk S.V. ― thoracic surgeon, postgraduate student of Clinical Anatomy and Operative Surgery Department namea after S.S. Mikhailov

11 Gagarin Pr., Orenburg, Russian Federation, 460021, tel. +7-922-829-50-92, e-mail: pinchuksergei@yandex.ru

 

Abstract

Investigation of intralung lymphatic nodes in routine practice is not uses. However its metastatic involvement influences the prognoses of the disease and information about it helps to change the treatment approach.

Objective. Investigation of metastasing in to intraorgan lymphatic nodes and evaluate its role in treatment of patients with primary lung cancer.

Material and methods. 60 lungs were investigated using large histotopographic sections. Analysis of data was held by use of Adobe Photoshop version 12.0.1 program. Statistical processing of the results of investigation was made by use of Statistica 10.0 program.

Results. Metastasing in to intraorgan lymphatic nodes was diagnosed in 31 patient (51,7%). Data about anatomic changes of lymphatic nodes structure after its metastatic involvement have been presented. Differences in overall survival of lung cancer treatment in dependence of lymphatic nodes metastatic status and the stage of metastatic involvement have been shown.

Conclusion. In those patients without metastasis in lymphatic nodes the overall survival was the best. Skip metastasing is associates with worse indices of overall survival. 

Key words: lung cancer, lymphatic nodes, large histotopographical sections.