Introduce. In the recent years for endometrial cancer patients with favorable prognosis had achieved positive results in treatment with tendency to decrease in adjuvant activity. For high risk patients the level of regional and distant relapses is retained high ― 20-30%, even with chemoradiotherapy after surgical treatment. It’s also associated with inadequate lymphadenectomy like very important diagnostic tool. In this connection, we have studied the efficacy of modified method of chemoradiotherapy with prophylactic irradiation of paraaortic lymph nodes for II-III FIGO stage patients in our investigation.