Abstract. Department of radiology Chkalov (formerly Orenburg) medical Institute was established in the year of Foundation of the regional oncologic dispensary in 1946. In 1956, it was headed by the first Professor radiologist A.V. Grigorieva. Heads of Department was a soldier-a decorated associate Professor L.I. Temkin; after combining with the course of Oncology ― associate Professor B.D. Ryabov, Professor A.A. Shtil. Currently the Department is headed by Professor A.G. Schekhtman. The main scientific directions of the Department ― improvement of methods of intravital imaging in tumors of various localizations, the development of microsurgical techniques during surgical interventions, the introduction of endoscopic techniques for the treatment of malignant neoplasms, palliative care in Oncology. In unworthy time the Department employs 14 people, including 3 doctors of medical Sciences, Professor.
Number 4 (26) 2016
THE ONCOLOGY SERVICE OF THE ORENBURG REGION FOR 70 YEARS
Abstract. History of the Orenburg Oncology service begins in November 1946, when, on the basis of hospital №1658 opened a hospital for 20 beds, and the intake of cancer patients was carried out in the regional clinic. The organizer of this work were B.A. Soloveychik, a brilliant surgeon and chief doctor of the clinic until 1959 In subsequent years, chief physician of Orenburg cancer center was Honored doctor of the Russian Federation A.M. Kochetkov, V.N. Kirsanov. Currently, the clinic is headed by candidate of medical Sciences A.V. Klimushkin. Highly qualified team OOCOD, having the latest equipment allows the entire range of diagnostic and therapeutic interventions to cancer patients in Orenburg region at a high modern level.
HIPPEL ― LINDAU DISEASE
Abstract. Clinical observation of autosomal dominantly inherited disorder ― von Hippel ― Lindau disease are shown in the article. The disease is characterized by the development of various tumors including tumors of the retinal and central nervous system, haemangioblastomas, clear cell renal carcinoma and phaeochromocytomas. It was noted the clinical manifestations of the disease, the distinctive features of diagnosis and treatment.
CLINICAL APPLICATION OF MICROSURGICAL ANASTOMOSIS ESOPHAGEAL-GASTRIC RESECTION OF THE ESOPHAGUS AND GASTRIC CARDIA
Abstract. The article presents an analysis of 160 cases of clinical application of microsurgical esophago-gastric anastomosis in resection of the esophagus and gastric cardia in the work of the surgical thoracic Department of the Orenburg regional clinical Oncology dispensary during the period 2009-2016.
ASPECTS OF CLINIC, DIAGNOSTIC AND TREATMENT OF MULTIPLE PRIMARY AND METASTATIC LUNG CANCER
Abstract. A retrospective analysis of 150 outpatients of patients who have received prior treatment for malignant tumors of various localizations. In those patients the round shadows were revealed in the lung at different times after treatment. Patients were divided into two groups: 85 patients with multiple primary lung cancer and 65 patients with metastatic lung lesion. Thus, received data indicate that the first stage and localization of tumor are important characteristics that can be used for differential diagnosis of primary multiple and metastatic lung tumors. Considering that the exact diagnosis can be established only after the histological conclusion we consider that surgical step should be mandatory when primary multiple and metastatic lung tumors are suspected.
ENDOSCOPIC DIAGNOSIS OF MELANOMA OF THE UPPER GASTROINTESTINAL TRACT
Abstract. The article summarizes the world literature about endoscopic diagnosis of rare disease ― primary melanoma upper gastrointestinal tract and secondary lesions of the gastrointestinal tract in its disseminated form. Analyzed data of observations of patients with melanoma from 2005 to 2015 at the N.N. Blokhin Russian Cancer Research Center. The most interesting clinical case was demonstrated.
GROWTH FACTORS OF VEGF FAMILY IN TISSUES OF ESOPHAGEAL SQUAMOUS CELL CANCER AND ESOPHAGEAL ADENOCARCINOMA
Introduction. Study of the biological nature of cancer can give interesting information about process course and contribute to drug therapy development.
POSSIBILITIES OF SURGICAL TREATMENT OF PATIENTS WITH MALIGNANT TUMORS OF THE VULVA OF REPRODUCTIVE AGE
Abstract. Malignant neoplasms of the vulva are rarely encountered tumors in women. In recent decades have seen an increase in the proportion of patients with cancer of the vulva under the age of 40 years. The analysis of the results of the special treatment of patients with malignant neoplasms of the vulva, treated at Orenburg Regional Clinical Oncology Center for the period from 2005 by 2015, at the age of 40 years. The main method of treatment is surgical technique. Use of reconstructive plastic surgery in the surgical treatment of cancer vulvar helped to improve the results of special treatment, fewer postoperative complications and improve the quality of life of patients. Three of the patients after treatment came four pregnancies ended the birth of full-term infants. The two women were executed caesarean section, gave birth one yourself vaginally.
SURGICAL TREATMENT OF THE LUNG CANCER AFTER NEOADJUVANT CHEMOTHERAPY
Abstract. The results of the surgical treatment of 48 patients with lung cancer treated and not treated by the neoadjuvant chemotherapy were presented in the article. It is shown that the neoadjuvant chemotherapy allows to achieve the increasing of resectability of the tumor in patients with locally advanced forms of the lung cancer as well as it increases the proportion of the organ preservation surgery and does not impair the during of the early postoperative period and long-term results of the treatment.
EFFICIENCY OF ENDOBRONCHIAL ULTRASONOGRAPHY IN THE DIAGNOSIS OF PERIPHERAL LESIONS OF LUNGS
Objective. To evaluate the effectiveness of endobronchial ultrasonography in the diagnostics of peripheral lesions of lungs. The analysis included 114 patients (69 men and 45 women) who underwent endobronchial ultrasound study using radial mini-probe (scanning frequency 20 MHz) with subsequent transbronchial biopsy of visualized lesions in lungs. Using the radial mini-probe entered into operator channel of bronchoscope, we managed to visualize pathological lesions and to perform transbronchial biopsy of lungs in 100 out of 114 cases. Total effectiveness of transbronchial biopsy of lungs was 88% (88 14 patients (20.9%) the material was not informative. Endobronchial ultrasonography is an effective method for visualization of peripheral neoplasms of the lungs. Prognostic factors of biopsy effectiveness are: size of the lesion ˃20 mm, presence of draining bronchus based on CT data, central position of mini-probe relative to the lesion.