O.A. Malikhova, L.V. Cherkess, R.S. Savosin
N.N. Blokhin National Medical Research Center of Oncology of the MH of RF, Moscow
Malikhova O.A. ― D. Sc. (Medicine), Professor, Head of Endoscopic Department of the N.N. Blokhin National Medical Research Center of Oncology of the MH of RF
23 Kashirskoe highway, Moscow, Russian Federation, 115478, e-mail: malikhova@inbox.ru
Abstract
The aim of the work was to evaluate the use of endobronchial ultrasonography with fine needle puncture of mediastinal lymph nodes for the diagnosis of peripheral lung cancer. The study included 56 patients (29 men and 27 women) who underwent endobronchial ultrasound followed by a transbronchial biopsy of a group of lymph nodes. The obtained material was investigated using liquid Cytology in case of transbronchial puncture. The results of morphological conclusions were divided depending on the size of the punctured lymph nodes and the accuracy of the obtained material. The best efficiency of tumor lesion verification was achieved with lymph node puncture of 1.5-3 cm (46%) and more than 3 cm (78%). When the size of the lymph nodes is less than 1.5 cm, it was not possible to obtain morphological confirmation in any of the cases. Thus, endobronchial ultrasonography is a well-established minimally invasive method for N-staging lung cancer in mediastinal lymph nodes. The accuracy of obtaining the material by fine needle puncture under endobronchial navigation depends largely on the size of the affected lymph node.
Key words: endobronchial ultrasonography, peripheral lung formations, transbronchial biopsy.