MODERN ISSUES OF IMPACT CHEMOTHERAPY AND RADIOTHERAPY ON CARDIOVASCULAR SYSTEM IN ONCOLOGY PATIENTS

A.F. Khalirakhmanov1,2, E.A. Gaziev2, S.V. Zinchenko1,2, N.I. Bariev1, A.Z. Sharafeev2, I.V. Ryabchikov1

1Kazan Federal University, Kazan

2University Hospital, Medical part of Kazan Federal University, Kazan 

Khalirakhmanov A.F. — PhD, Doctor of the Department of X-ray diagnostic methods and treatment of University Hospital, Medical part of Kazan Federal University

1a Chekhov Str., Kazan, Russian Federation, 420043, e-mail: ai.bolit@mail.ru

 Abstract. Breakthrough in oncology over the last years improved oncology patient’s survival. This was achieved through the early diagnosis and effective treatment by modern chemotherapeutic agents. However, new challenges have emerged. Patients may experience adverse cardiovascular events related to their oncology treatment or as a result of an exacerbation of underlying cardiovascular disease. The article describes the various pathophysiological aspects of chemotherapy treatment and radiotherapy that impact on the onset and progression of cardiovascular diseases.

Key words: cardio-oncology, coronary heart disease, cardiotoxicity, chemotherapy, radiotherapy.