A.M. Fedun, O.V. Dyukova, E.N. Bogush-Vishnevskaya, D.P. Korotin, P.A. Marusov, O.V. Zhelezin, R.G. Pegov
Nizhny Novgorod Regional Clinical Oncology Center, Nizhny Novgorod
Fedun A.M. ― PhD (medicine), head of Thoracic Surgical Department of the Nizhny Novgorod Regional Clinical Oncology Center
1 Ankundinovskoe highway, Nizhny Novgorod, 603081, tel.: (831) 465-15-41, +7-951-902-96-24, e-mail: fedun@mail.ru
Abstract. Мediastinoscopy is the gold standard for obtaining samples of lymph nodes, for the purpose of morphological diagnosis of the pathology of the mediastinal organs. It can be used for suspected lymphogenous metastasis of verified lung cancer for the purpose of N-staging, with previously unconverted lung cancer for verifying lung cancer and determining the stage for the diagnosis of isolated mediastinal lymphadenopathy. In the literature there is a small number of reports on the use of this study in the thoracic departments of Russia is available in the literature.
The purpose of our study is to report on our experience of using cervical mediastinoscopy.
The study analyzed 279 patients who underwent cervical mediastinoscopy in our clinic from 2014 to 2016 inclusive.
Indications for cervical mediastinoscopy were: determination of the stage of malignant process ― 156 (61%) patients, sarcoidosis ― 75 (30%) patients, nonspecific lymphadenopathy ― 10 (4%), lymphoproliferative diseases ― 9 (3.5%), tuberculosis ― 4 (1.6%), myeloma ― 1 (0.4%) patient. There were 184 men (66.2%), women ― 94 (33.8%). The distribution by age in this group is from 25 years to 81 years. The average age of patients was 55.9 years. The most common biopsy of level 4 lymph nodes for staging lung cancer was 137 (88%) and 2 levels for the diagnosis of sarcoidosis ― 47 (63%).
Neck mediastinoscopy is a highly informative method of diagnosing the mediastinal pathology. Its widespread use, along with the development of other miniinvasive methods for obtaining tissue samples from the mediastinal lymph nodes, indicates its superiority, especially in lung cancer and isolated mediastinal lymphadenopathy.
Key words: mediastinoscopy, lung cancer, mediastinal lymphadenopathy.