I.Y. Nedoluzhko, S.S. Kazakova, K.V. Shishin, N.A. Kurushkina, Yu.V. Embutnieks, E.R. Valitova, O.I. Berezina, O.S. Vasnev, M.A. Koshkin, N.V. Orlova, M.V. Pavlov, Yu.V. Vyazhevich

A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow

The Loginov Moscow Clinical Scientific Center, Moscow

Shishin K.V. ― Professor of the Department of Faculty Surgery №2 of the A.I. Evdokimov Moscow State University of Medicine and Dentistry, Head of Endoscopy Department of The Loginov Moscow Clinical Scientific Center

86 Enthusiasts highway, Moscow, Russian Federation, 111123, tel.: (495) 304-30-35 доб. 1451, +7-926-211-34-68, e-mail:

Abstract. Achalasia is a motility disorder of the esophagus with a prevalence of 1:100,000. It is characterized by absence of esophageal peristalsis and by impaired lower esophageal sphincter (LES) relaxation in response to swallowing. The most common primary symptom is dysphagia to both solids and liquids with gradual symptom progression. Peroral endoscopic myotomy (POEM) is a novel, incisionless, minimal invasive endoscopic surgical procedure, which has been derived from the era of natural orifice transluminal endoscopic surgery (NOTES), intended for long-term recovery from symptoms of esophageal achalasia.

Key words: achalasia, Heller myotomy, laparoscopic myotomy, peroral endoscopic myotomy, POEM, diseases of the esophagus.